Before we begin

NEURON is using .mod files to specify channels and dynamics. You can read about .mod files and how they are created and specified in:

NMODL — NEURON 7.7 documentationwww.neuron.yale.edu

RSME is using various membrane mechanisms. One of them is GradSyn, which we used to model SAC-SAC synapses. You can download RSME's .mod files in:

27KB

mods.zip

archive

Open

Unzip the mods directory to your project folder. Now you will have to compile the files to work with NEURON. To do so, go to the Terminal, get into your project folder, and enter:

nrnivmodl \mods

It will create a new folder (in Mac in will be x86_64), in which the compiled C files.

Compiling these files is important. You will not be able to proceed with this example without it.